CBD Oil Side Effects on Kidneys. What Studies Did We Find?

5 Mar, 2022 | Joe | No Comments

CBD Oil Side Effects on Kidneys. What Studies Did We Find?

The two main threats to kidney function are kidney injury and chronic kidney disease. Kidney health issues can, depending on the cause and severity, affect your quality-of-life.

Conventional treatments have been around a while and some are quite effective. These treatments can have adverse side effects, which can make them unaffordable. People suffering from chronic kidney disease or severe kidney injury may look beyond mainstream options.

In the last few years, cannabinoid medication has seen an explosion. Millions of people are claiming that CBD (cannabidiol) helped with their symptoms.

How can CBD oil be used to treat chronic kidney disease (or any other kind of renal disease)? It is a complicated topic, and there are more questions than answers.

What is CBD Oil exactly?

CBD oil is what you most likely know if CBD is something that you are familiarized with. The oil brand will determine the content and potency. CBD oil is a form of natural extract from all forms of cannabis Sativa L..

The manufacturing process of extracting CBD and other compound compounds includes alcohol, hydrocarbon or CO2. Once the CBD has separated, it can be infused into carrier oil like MCT or grapeseed, hemp, coconut, or even coconut.

Then you will consume a pre-measured quantity based your CBD dose requirements. CBD oil has side effects. While CBD oil claims to relieve symptoms, some people don’t realize that CBD can cause them. We’ll talk about that in a moment.

How CBD is absorbed into your body

CBD is absorbed through an extensive internal network called the endocrinoid system. The ECS comprises specific pathways known to be the CB1 (central nervous) and CB2 (peripheral) receptors.

THC, one of the cannabinoids found in cannabis, is able to bind to both CB1 and CB2, resulting in mental and bodily effects for recreational or medical users.

CBD is an exception. Although CBD interacts with one receptor, other cannabinoids do not interact with it. Instead, CBD impacts other receptors as well as pathways, eventually altering the CB1 receptor’s shapes.

This reaction alters the way that external (phytocannabinoids), but also internal (endocannabinoids), can affect the brain or body. These “adjustments”, which CBD interacts with the serotonin or vanilloid receptors, can often be beneficial.

CBD must first be absorbed into your bloodstream. There are many different ways to do this. Each consumption method has its pros and cons, which can affect the strength, duration and effects of CBD.

Persons with chronic kidney disease or other diseases should also be aware of potential drug interactions.


Inhalation gives you a more authentic vape experience. CBD quickly hits the bloodstream when inhaled. In this way, you can feel the effects in just minutes. However, the effects typically last two to four times as long as other methods.

Many vendors won’t allow you to inhale products. We’re all familiar with the vape sickness epidemic. It dominated the news this year (and continues to dominate the news today). It is also unknown how long-term the effects of smoking burnt cannabis plant material, even though it appears to be safer than tobacco.


CBD can also be taken orally. Cannabidiol is able to be infused into hundreds of food and beverages. Here are some examples.

CBD is most easily broken down in our livers after we inhale. CBD is slowest acting when consumed as food or drinks. It lasts for eight hours, longer than any other method.


Topicals form another category of CBD Products . But, unlike smoking and eating topicals won’t reach your bloodstream. These products deliver a faster, more targeted effect by being applied directly onto the skin.

Is CBD Oil Extracted through the Kidneys

We know where CBD enters the body. But how does it leave? One would assume that urine tests could detect drug use. However, the kidneys can remove large amounts of THC and CBD. But, a 2019 analysis in the Canadian Journal of Kidney and Health Disease proves that nothing could be further off the truth.

THC, CBD, and other psychoactive substances mostly exit the feces. They feel CBD’s relatively minor effects on the renal system don’t warrant a CBD dosage adjustment. However, it is not clear if other minor cannabinoids are removed in the exact same way.

What are the Side Effects from CBD Oil Oil?

CBD oil is safe to use and has no addictive potential. CBD oil has no side effects, and is much less expensive than prescription medication. You might not find CBD oil to be beneficial for your health. Keep an eye on these side effects.

  • Dry mouth
  • Appetite change
  • Nausea
  • Fatigue
  • Insomnia
  • Dizziness
  • Diarrhea

CBD in high doses is more likely to cause the effects, particularly if it’s given quickly without any titration. Stop using CBD if the symptoms continue or get worse.

CBD extracts should not get you high, as hemp oil contains minimal to no tetrahydrocannabinol. If you feel intoxicated it could be because the manufacturer mislabeled the product.

Common Causes for Kidney Disease

The National Institute of Diabetes and Digestive and Kidney Diseases says that chronic kidney diseases (CKD) are usually caused Diabetes or High Blood Pressure.

However, there are many more reasons.

  • Drug interactions
  • Poison
  • Infection
  • Physical injury
  • Genetics

Kidney Disease Symptoms

Since kidney disease is caused by many common infections, toxins and other factors, it can be hard to determine the cause. These signs may be more noticeable if you have diabetes and high blood pressure.

  • Nausea and vomiting
  • Back pain
  • Urine volume increase or decrease
  • Fatigue
  • Sleep issues
  • Muscle cramps
  • Itchy or dry skin
  • Swelling at the ankles and feet
  • Chest pain
  • Breathing difficulty
  • Hypertension (higher blood pressure).

The serious danger to kidney function is chronic kidney disease. Discuss your concerns with your doctor as soon as you can.

Do CBD Oil and Kidneys Hurt?

While CBD oil may damage the kidneys in some cases, it might also benefit renal function. Preliminary research indicates that the results of preliminary research are either positive, negative, or inconclusive.

Next, we’ll take a look at all the results.